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Laboratory homogenizers and their applications

Laboratory homogenizers are very useful equipment, since they allow the process of homogenization of different types of materials, such as tissues, food, plants and other biological or chemical elements.  Nowadays there are different models of laboratory homogenization, each one of them with specific functions and applications.

The main function of any homogenizer is to mix an experimental sample with the solution or solvent to achieve the solution required for a test or experiment. However, homogenizers used in the laboratory are classified differently. Traditional laboratory homogenizers are usually fluidized bed, rotor-stator and ultrasonic homogenizers.

What is a laboratory homogenizer used for?

Homogenizers are common in clinical and research laboratories. In cell culture and microbiology laboratories, they are usually used to suspend cells. In a clinical laboratory, it can be used to mix reagents from an assay or to mix an experimental sample and a diluent.

Laboratory homogenizers are used to ensure that all components of the prepared suspensions have the same characteristics. They are also used for gentle mixing and rapid and accurate resuspension of cells and chemical and biological fluid components in tubes. Since homogenization is a key process in the preparation of samples of biological origin, prior to analysis of nucleic acids, proteins, cellular studies, metabolism, and pathogens. Homogenizers are vital and useful in most food and beverage, cosmetic, science and technology industries, as well as in many other industries where the manufacturing process must be combined and emulsified.

Fluidized-bed homogenizer

This type of homogenizer works with a process in which an upstream of fluid that can be liquid, gas or both, suspends the solid particles, which behave as a fluid. This homogenizer is commonly found in models of large sizes, which often represents an inconvenience for laboratories, because in these the space is always limited.

Fluidized-bed technology is a key technology. These equipment are useful in the food, dairy, chemical and pharmaceutical industries. They are used in drying or cooling particles (powders, agglomerates or pills) and in the production of agglomerates and granules from fine powders. The fluidized bed is designed for products that float on an air or gas mattress. The air is supplied by a special perforated distribution plate and flows through the solid bed at a speed sufficient to support the weight of the particles in a fluidized state. Bubble formation and collapse of bubbles within the fluidized material bed favor intense particle movement. In this state, solids behave as free-flowing boiling liquids.

Rotor-stator homogenizer

A rotor-stator homogenizer is a device with a system designed to achieve optimal homogenization due to a rotor with blade that rotates in a steady state at high speed with holes, where the fluid moves. It also allows in many cases multiphase configurations of rotors and stators and special ultrafine meshes that provide high intense shear, further reducing the homogenization times by reducing the number of recirculation steps required.

It usually consists of a rotating turbine cutter and a high-speed rotor/stator. The head of the rotor-stator is placed in the lower center of the mixing vessel to allow it to be used with very small volumes of material. During the operation of this type of homogenizers, the external turbine is mixed and rotated to the right and moves the materials from the wall of the container and upwards. The inner sheets rotate to the left and move the material down and into the head for high-speed homogenization. They are made in many sizes from 10 with 4000 liters capacity. They have great applicability in the pharmaceutical and cosmetic industries to mix viscous materials, being a very useful equipment to homogenize, emulsify, dispersion and particle size reduction. Among its main uses are antacids, biopolymers, collagen solutions, dental compounds, gelatin compounds and gels.

Ultrasound homogenizer

Ultrasonic homogenizers are useful tools for mixing and homogenizing liquid-solid and liquid-liquid suspensions. Ultrasonic homogenization is achieved by reducing particles in a liquid so that they become uniformly small and evenly distributed, through a mechanical process in which particles in a liquid are reduced, with the aim of obtaining uniformity in their size and distribution (improving product stability).

This type of homogenizers are found for both laboratories and industrial scale, they come in various sizes to suit your need. Among its main applications are in the fields of biology, chemistry, environment, analysis laboratories and research. Since this team enables the disintegration of biological cells and tissues for the extraction of proteins, DNA, and RNA.

What does Kalstein offer you?

Kalstein is a company MANUFACTURER of medical and laboratory equipment of the highest quality and the best technology at the best PRICES in the market, so you can make your PURCHASE confidently with us, knowing that you have the service and advice of a company specialized in the field and committed to provide you with safe, economical and effective options to perform your functions in the right way.

This time we present our Ultrasonic Homogenizer YR05015 // YR05020. This cutting-edge technology equipment has the following features:

  • Single chip technology + 4.3-inch capacitive TFT touch screen (optional 7-inch), optional computer communication or data printing;
  • PID control, ultrasonic time, power can be set from 1% to 100%.

For more information we invite you to check HERE