To treat chemotherapy drugs are used that are highly dangerous, and require a series of precautions to be processed and administered, so when choosing a laminar flow hoods to prepare these medicines, we must take into account that they can cause harm to other people exposed to them, to people who handle chemotherapy drugs.
Due to the high degree of contaminants these chemotherapy drugs can have, the equipment used must meet the requirements for the protection of products, personnel and the environment. In the case of the preparation of cytostatics are drugs for chemotherapies with very diverse mechanisms of action, but with the common feature of interrupting the cell cycle in some of its phases.
Vertical Laminar Flow hoods.
The vertical laminar flow hoods is a cockpit where vertical air flow occurs, curtain type, in which the microparticles and aerosols produced by handling cytostatics are prevented from leaving outside and not contaminating the staff and the working environment, thus creating a kind of barrier between the work area where the drug is being manipulated and the outside where the worker who is handling the material is located.
This is produced by an aspiration system that absorbs and collects the contaminated air and then is passed by some filters, one part is returned to the middle and the other is expelled to the outside. In addition, it features HEPA (High Efficiency Particulate Air) filters that are used to remove harmful particles with 99% efficiency, and a short-wave UV light lamp for sterilization of the work area.
Specific recommendations for chemotherapy use booths.
Although vertical laminar flow hoods , they have features and designs that are optimal for working plant tissue culture, media plate preparation, electronic material inspection, medical device assembly and conducting polymerase chain reaction experiments, thanks to their HEPA filter being placed on top of the hoods, so the unidirectional air flow moves through vertical parallel lines. They have a transparent protective screen that covers the top front of the screen.
There are certain microorganisms, cytotoxic products that should be used biological safety cabins that are similar in design to vertical laminar flow hoods , but have in the air outlet the same HEPA filters that retain contaminants, achieving the protection of the chemical material used in chemotherapy, the operator and the environment. For the preparation of chemotherapeutic agents, the use of class II Biological Safety Cabins is recommended. In KALSTEIN we offer the YR series suitable for these applications, visit us at HERE
Importance of class II biological safety cabin in chemotherapy.
Chemotherapy should be germ-free, so that the patient is not at risk of infection when given the medicine. That’s why chemotherapy must be prepared inside a laminar flow hoods called the Biological Safety Cabin. Chemotherapy should be prepared under medical indications very precisely, there should be no margin for error; it should be prepared at the time it is to be used as this also ensures sterility and accuracy.
Chemotherapy is being prepared inside this booth, for two important reasons. The first is to maintain the preparation of sterile chemotherapy and the second reason is to limit the contact between the particles of chemotherapy and the personnel handling the apparatus and medicines, since these drugs are potentially dangerous to the health of the personnel handling them and the environment.
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